Heparin Half Life at Life

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Heparin Half Life. The volume of distribution of heparin is then, under most circumstances, limited to the plasma volume. It is significantly longer for lmw heparin than for unfractionated heparin.

PPT Coagulation Modifier Drugs PowerPoint Presentation
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Appears to be removed from the circulation mainly by the reticuloendothelial system and may localise on arterial venous endothelium. The fate of heparin in rabbits after intravenous injection. Heparin binds reversibly to its target sites of action, antithrombin and the other serine proteases involved in coagulation, especially activated factor x.

PPT Coagulation Modifier Drugs PowerPoint Presentation

The volume of distribution of heparin is then, under most circumstances, limited to the plasma volume. It is significantly longer for lmw heparin than for unfractionated heparin. Heparin binds reversibly to its target sites of action, antithrombin and the other serine proteases involved in coagulation, especially activated factor x. Heparin is cleared via a dual mechanism.